Factor XIIa
《英文msh詞典》Factor XIIa
[主題詞] Factor XIIa
[同義詞] Coagulation Factor XIIa
[同義詞] Factor XII,Activated
[入口詞] Activated Factor XII
[入口詞] Blood Coagulation Factor XII,Activated
[入口詞] Hageman-Factor Fragments
[入口詞] Prekallikrein Activator
[入口詞] Activator,Prekallikrein
[入口詞] Factor XIIa,Coagulation
[入口詞] Fragments,Hageman-Factor
[入口詞] Hageman Factor Fragments
[入口詞] XIIa,Coagulation Factor
[中文釋義] 因子Ⅻa
[英文釋義] Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation,kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein,plasmin,and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.